INTEGRATED DIAGNOSTIC TECHNIQUE FOR BACTERIAL INFLAMMATORY PROCESS IN VULVA AND VAGINAL IN GIRLS AGED 0 TO 8 YEARS Russian patent published in 2015 - IPC G01N33/68 

Abstract RU 2563182 C1

FIELD: medicine.

SUBSTANCE: biological material is sampled from the patient by smearing a lateral wall of a vaginal mucosa behind a hymen, and a real-time PRC is conducted to analyse a qualitative and quantitative microbial count and a CD45 gene mRNA expression level. A bacterial inflammatory process in vulva and vagina of girls aged 0 to 8 years is diagnosed if genome equivalents appear to fall within the preset range per a microbial sample, whereas CD45 gene mRNA makes min. 0.5 units in relation to reference genes.

EFFECT: invention provides the integrated assessment of the vaginal mucosal microbiota together with an inflammatory reaction marker by using quantitative real-time PCR technique.

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RU 2 563 182 C1

Authors

Batyrova Zalina Kimovna

Uvarova Elena Vital'Evna

Donnikov Andrej Evgen'Evich

Burmenskaja Ol'Ga Vladimirovna

Trofimov Dmitrij Jur'Evich

Dates

2015-09-20Published

2014-04-11Filed