METHOD FOR DETECTING TYPE 1 DIABETES MELLITUS Russian patent published in 2021 - IPC A61B10/00 G01N33/68 G01N33/74 G01N33/92 G01N33/573 G01N30/06 G01N30/72 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to clinical diagnostics, and can be used to identify type 1 diabetes mellitus in pregnant women. A patient's blood sample is taken; a sample of the patient's blood is prepared to obtain an analyte; the content of Angiotensinogen and/or Apolipoprotein C-III and/or Vitronectin is determined as a marker of type 1 diabetes mellitus in the analyte. If the relative content of Angiotensinogen is not less than 1.29% of the total protein content in the analyte and/or if the content of Apolipoprotein C-III is not less than 2.91% of the total protein content in the analyte and/or if a patient has no diagnosis of "obesity" and the content of Vitronectin is not more than 0.71% of the total protein content in the analyte, type 1 diabetes mellitus is identified. Identification of the content of the marker of type 1 diabetes mellitus in the analyte is carried out by the method for enzyme immunoassay or by chromatography-mass spectrometry.

EFFECT: method provides an increase in the accuracy of analysis in the diagnosis of type 1 diabetes mellitus in pregnant women, as well as an expansion of the arsenal of existing methods for analysis in the diagnosis of type 1 diabetes, by identifying the content of at least one marker of type 1 diabetes mellitus in the analyte by enzyme immunoassay or chromatography-mass spectrometry.

2 cl, 8 tbl, 3 ex