FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to clinical diagnostics, and can be used to identify type 1 diabetes mellitus in pregnant women. A patient's blood sample is taken; a sample of the patient's blood is prepared to obtain an analyte; the content of Angiotensinogen and/or Apolipoprotein C-III and/or Vitronectin is determined as a marker of type 1 diabetes mellitus in the analyte. If the relative content of Angiotensinogen is not less than 1.29% of the total protein content in the analyte and/or if the content of Apolipoprotein C-III is not less than 2.91% of the total protein content in the analyte and/or if a patient has no diagnosis of "obesity" and the content of Vitronectin is not more than 0.71% of the total protein content in the analyte, type 1 diabetes mellitus is identified. Identification of the content of the marker of type 1 diabetes mellitus in the analyte is carried out by the method for enzyme immunoassay or by chromatography-mass spectrometry.
EFFECT: method provides an increase in the accuracy of analysis in the diagnosis of type 1 diabetes mellitus in pregnant women, as well as an expansion of the arsenal of existing methods for analysis in the diagnosis of type 1 diabetes, by identifying the content of at least one marker of type 1 diabetes mellitus in the analyte by enzyme immunoassay or chromatography-mass spectrometry.
2 cl, 8 tbl, 3 ex
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Authors
Dates
2021-07-26—Published
2020-06-09—Filed