FIELD: medicine.
SUBSTANCE: invention relates to medicine, in particular cardiovascular surgery and angiology, and can be used in the treatment of patients with obliterating atherosclerosis of the arteries of the lower extremities, also known as peripheral artery diseases (PAD) of atherosclerotic etiology. A method for predicting fatal outcomes in patients with obliterating atherosclerosis of the lower extremity arteries of stages IIB - IV after endovascular reconstructions consists in determining markers of endothelial dysfunction in peripheral venous blood a day before endovascular interventions are performed: the activity of von Willebrand factor, the level of nitric oxide II metabolites and assessing the presence or absence of hypertension, followed by calculating the probability of developing a fatal outcome within a year after surgery according to the formula P = 1 / (1 + e-Z), where P is the probability of a fatal outcome in %, e is the base of the natural logarithm (Euler number), and Z is an indicator calculated as follows: Z = -46.16 + 0.021 * X1 + 0.209 * X2 + 8.471 * X3, where X1 is the value of vWF activity, %; X2 is the value of NO metabolites, mcm/ml; X3 is the value reflecting the presence or absence of hypertension in the patient: binary variable 0 means no hypertension or 1 means there is hypertension.
EFFECT: invention provides prediction of fatal outcomes in patients with obliterating atherosclerosis of the arteries of the lower extremities after endovascular interventions on the main arteries of the lower extremities.
1 cl, 2 ex
