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2 753 529

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IPC

C01B25/32(2006-01-01)

A61K6/838(2020-01-01)

A61L27/12(2006-01-01)

(21) (22)

Application

2021100042, 2021-01-11

(24)

Start date

2021-01-11

(22)

Actual filing date

2021-01-11

(45)

Published

2021-08-17

(72)

Inventor

Bogdanova Ekaterina AnatolevnaNefedova Kseniya ValerevnaSkachkov Vladimir Mikhajlovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauki Institut Khimii Tverdogo Tela Uralskogo Otdeleniya Rossijskoj Akademii Nauk

METHOD FOR MANUFACTURING GRANULES FROM BIOACTIVE MATERIAL BASED ON HYDROXYAPATITE OR FLUORAPATITE Russian patent published in 2021 - IPC C01B25/32 A61K6/838 A61L27/12

Abstract RU 2753529 C1

FIELD: bioactive materials.

SUBSTANCE: invention relates to a method for manufacturing granules from a bioactive material based on hydroxyapatite or fluorapatite impregnated with gelatin, which can be used for the restoration of bone tissues. The method includes the processing of crystalline fluorapatite powder of the composition Ca₅(PO₄)₃F or a powder of crystalline hydroxyapatite of the composition Са₁₀(РO₄)₆(ОН)₂ with an aqueous solution of gelatin followed by drying. According to the invention, a layer of hydroxyapatite or fluorapatite powder evenly distributed over the surface of the bowl of a vibrating installation is irrigated with a 13-17% aqueous gelatin solution at a mass ratio of hydroxyapatite powder or fluorapatite powder and a 13-17% aqueous gelatin solution equal to 3-5:1, and the resulting mixture is processed under vibration conditions with a frequency of 200-300 с^-1 for 10-15 minutes.

EFFECT: ensures a simple method for producing granules with a composition close to bone tissue.

1 cl, 3 dwg, 2 ex

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RU 2 753 529 C1

Authors

Bogdanova Ekaterina Anatolevna

Nefedova Kseniya Valerevna

Skachkov Vladimir Mikhajlovich

Dates

2021-08-17—Published

2021-01-11—Filed