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(19)

RU

(11)

2 753 965

(13)

C2

(51)

IPC

C07K14/705(2006-01-01)

C07K19/00(2006-01-01)

C12N5/783(2010-01-01)

C12N5/10(2006-01-01)

C12N15/63(2006-01-01)

C12N15/85(2006-01-01)

C12N9/00(2006-01-01)

A61K35/17(2015-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2016136370, 2015-02-16

(24)

Start date

2015-02-16

(22)

Actual filing date

2015-02-16

(45)

Published

2021-08-24

(72)

Inventor

Kuper Lourens Dzh. N.Korngold Ana BeatritsRabinovich Brajan A.Singkh KhardzheetOlivares Sajmon

(73)

Holder

Bord Of Ridzhents, Dze Yuniversiti Of Tekhas Sistem

CHIMERIC ANTIGEN RECEPTORS AND THEIR PRODUCTION METHODS Russian patent published in 2021 - IPC C07K14/705 C07K19/00 C12N5/783 C12N5/10 C12N15/63 C12N15/85 C12N9/00 A61K35/17 A61P35/00 

Abstract RU 2753965 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to CD19 specific polypeptide of chimeric antigen receptor (CAR) encoded by DNA sequence with SEC ID NO:5, 1-1485 SEQ ID NO:5 nucleotides or 67-1485 SEQ ID NO:5 nucleotides; it can be used in medicine.

EFFECT: invention allows for obtaining T-cells targeted to CD19, which can be used for the effective therapy of CD19+ malignant neoplasms.

17 cl, 42 dwg, 2 tbl, 5 ex

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RU 2 753 965 C2

Authors

Kuper Lourens Dzh. N.

Korngold Ana Beatrits

Rabinovich Brajan A.

Singkh Khardzheet

Olivares Sajmon

Dates

2021-08-24—Published

2015-02-16—Filed

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