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2 754 791

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IPC

G01N33/53(2006-01-01)

C07K14/00(2006-01-01)

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Application

2020139102, 2020-11-30

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Start date

2020-11-30

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Actual filing date

2020-11-30

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Published

2021-09-07

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Inventor

Alatortseva Galina IvanovnaSidorov Aleksandr ViktorovichNesterenko Liubov NikolaevnaLukhverchik Liudmila NikolaevnaAmiantova Irina IlinichnaDotsenko Vera VasilevnaVorobev Denis SergeevichMilovanova Aleksandra VladimirovnaMikhailov Mikhail IvanovichKiuregian Karen KarenovichNurmatov Zuridin SharipovichKasymov Omor TilegenovichZhavoronok Sergei VladimirovichKrasochko Petr AlbinovichZverev Vitalii Vasilevich

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Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Nauchnoe Uchrezhdenie Institut Vaktsin I Syvorotok Im. I.I. Mechnikova»

MOSAIC RECOMBINANT POLYPEPTIDE CONTAINING FRAGMENTS OF HEPATITIS E VIRUS PROTEINS OF GENOTYPES 1 AND 3 IN ONE POLYPEPTIDE CHAIN, INTENDED FOR USE IN TEST SYSTEMS USED IN THE SERODIAGNOSIS OF HEPATITIS E Russian patent published in 2021 - IPC G01N33/53 C07K14/00

Abstract RU 2754791 C1

FIELD: biotechnology, immunology.

SUBSTANCE: a mosaic recombinant polypeptide containing fragments of the hepatitis E virus proteins ORF2 and ORF3 of genotypes 1 and 3 in one polypeptide chain is described. The product is designed for use in test systems used in the serodiagnosis of hepatitis E.

EFFECT: genetic engineering design containing fragments of the orf2 and orf3 genes of HEV 1 and 3 genotypes in one reading frame; the strain is a producer of a mosaic recombinant polypeptide with fragments of the ORF2 and ORF3 proteins of the HEV 1 and 3 genotypes as part of one polypeptide chain; a purified mosaic recombinant polypeptide with fragments of the ORF2 and ORF3 proteins of the HEV 1 and 3 genotypes as part of one polypeptide chain.

1 cl, 30 dwg, 9 tbl

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RU 2 754 791 C1

Authors

Alatortseva Galina Ivanovna

Sidorov Aleksandr Viktorovich

Nesterenko Liubov Nikolaevna

Lukhverchik Liudmila Nikolaevna

Amiantova Irina Ilinichna

Dotsenko Vera Vasilevna

Vorobev Denis Sergeevich

Milovanova Aleksandra Vladimirovna

Mikhailov Mikhail Ivanovich

Kiuregian Karen Karenovich

Nurmatov Zuridin Sharipovich

Kasymov Omor Tilegenovich

Zhavoronok Sergei Vladimirovich

Krasochko Petr Albinovich

Zverev Vitalii Vasilevich

Dates

2021-09-07—Published

2020-11-30—Filed