COMPOSITIONS AND METHODS FOR EXPRESSING SEVERAL BIOLOGICALLY ACTIVE POLYPEPTIDES FROM ONE VECTOR FOR THE TREATMENT OF HEART DISEASES AND OTHER PATHOLOGIES Russian patent published in 2021 - IPC C07K14/52 C07K19/00 C12N15/09 C12N15/62 A61K38/17 A61K48/00 A61P9/00

Abstract RU 2758489 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to polynucleotide for the expression of functional calcium-binding protein S100A1, stromal cell-derived factor-1α (hereinafter – SDF-1α) and vascular endothelial growth factor 165 (hereinafter – VEGF165); it can be used in medicine.

EFFECT: obtained polynucleotide allows for simultaneous expression of S100A1, SDF-1α and VEGF165; it can be used for the effective treatment of heart diseases.

19 cl, 33 dwg, 16 tbl, 14 ex

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RU 2 758 489 C2

Authors

Patel Dimki S.

Patel Amit N.

Dates

2021-10-28—Published

2016-11-11—Filed