Patenton — panteon of patents

(19)

RU

(11)

2 785 658

(13)

C2

(51)

IPC

C07K16/28(2006-01-01)

C07K16/30(2006-01-01)

C12N5/783(2010-01-01)

A61P35/02(2006-01-01)

(21) (22)

Application

2020140832, 2019-06-12

(24)

Start date

2019-06-12

(22)

Actual filing date

2019-06-12

(45)

Published

2022-12-12

(72)

Inventor

Abujoub, AidaFleming, TonyHuang, LuHong, ConnieBlankenship, JohnHolmberg, BrianZhang, ChonghuiBu, Dexiu

(73)

Holder

Novartis Ag

CHIMERIC ANTIGEN RECEPTORS FOR BCMA AND THEIR USE Russian patent published in 2022 - IPC C07K16/28 C07K16/30 C12N5/783 A61P35/02 

Abstract RU 2785658 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, in particular to an isolated chimeric antigen receptor (hereinafter – CAR), which binds to BCMA, as well as to an isolated nucleic acid molecule encoding it. A domain binding BCMA is also disclosed. The invention also relates to a cell and a vector containing the above-mentioned nucleic acid molecule.

EFFECT: invention is effective for provision of antitumor immunity, as well as for treatment of a subject, which has a disease associated with BCMA expression.

57 cl, 3 dwg, 18 tbl, 1 ex

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RU 2 785 658 C2

Authors

Abujoub, Aida

Fleming, Tony

Huang, Lu

Hong, Connie

Blankenship, John

Holmberg, Brian

Zhang, Chonghui

Bu, Dexiu

Dates

2022-12-12—Published

2019-06-12—Filed

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