FIELD: pharmaceutics.
SUBSTANCE: invention relates to conjugates of peptide or peptidomimetic containing or consisting of a targeting sequence selected from a group consisting of SEQ ID NO: 24 and 25, wherein peptide or peptidomimetic is cyclic or has length of no more than 30 amino acids, and peptide or peptidomimetic is related to a component selected from a biologically active component and a diagnostic component. The conjugate is suitable for targeting a biologically active component or a diagnostic component to muscle cells. Such a biologically active or diagnostic component can be, for example, oligonucleotide, small interfering RNA, a gene, a virus, a protein, a drug, a small organic molecule, a pharmaceutical preparation or a detectable agent.
EFFECT: conjugate can be used, for example, to treat a muscle cell-related disorder.
20 cl, 17 dwg, 2 tbl, 6 ex
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Authors
Dates
2021-11-08—Published
2017-11-15—Filed