APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIALKYL-2-THIOXO-1,3,6-TRIAZASPIRO[4.4 NON-8-ENE-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY Russian patent published in 2021 - IPC A61K31/407 A61K31/4188 A61P31/04 

Abstract RU 2763731 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to the field of pharmacology, namely the use of 9-aroyl-8-hydroxy-6- (2-hydroxyalkyl)-1,3-dialkyl-2-thioxo-1,3,6-triazaspiro[4.4]non-8-en-4,7-diones of the general formula indicated below, where R1=Н, R2=Н, Ar=С6Н4СН3-4; R1=Н, R2=Ph, Ar=C6H4Br-4; R1=СН3, R2=Bu, Ar=Ph.

EFFECT: antimicrobial activity of spiro compounds of the structure indicated below.

1 cl, 1 tbl, 4 ex

Similar patents RU2763731C1

Title Year Author Number
THE USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONES AS AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS 2022
  • Maslivets Andrei Nikolaevich
  • Tretiakov Nikita Alekseevich
  • Balandina Svetlana Iurevna
RU2790379C1
USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONES AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS CULTURE 2023
  • Tretiakov Nikita Alekseevich
  • Maslivets Andrei Nikolaevich
  • Balandina Svetlana Iurevna
RU2813484C1
USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-4,7-DIONES AS AGENTS WITH ANALGESIC ACTIVITY 2023
  • Maslivets Andrei Nikolaevich
  • Kobelev Aleksandr Ivanovich
  • Makhmudov Ramiz Ragibovich
RU2810074C1
9-AROYL-8-HYDROXY-6-(2-HYDROXYETHYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONS, HAVING ANALGESIC ACTIVITY, AND A METHOD FOR PRODUCTION THEREOF 2019
  • Tretyakov Nikita Alekseevich
  • Maslivets Andrej Nikolaevich
  • Makhmudov Ramiz Ragibovich
  • Maslivets Anna Andreevna
RU2707197C1
APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-IMINO-1-THIA-3,6-DIAZASPIRO[4,4]NON-8-EN-4,7-DIONES AS AGENTS, WITH ANTIMICROBIAL ACTIVITY 2022
  • Maslivets Andrei Nikolaevich
  • Tretiakov Nikita Alekseevich
  • Balandina Svetlana Iurevna
RU2790479C1
METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-3-PHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES HAVING ANTIMICROBIAL ACTIVITY 2021
  • Maslivets Andrej Nikolaevich
  • Balandina Svetlana Yurevna
  • Kobelev Aleksandr Ivanovich
  • Babikova Natalya Vladimirovna
RU2767558C1
APPLICATION OF 9-AROYL-8-HYDROXY-6-[2-(HYDROXYMETHYL)PHENYL]-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-EN-4,7-DIONE AS AN AGENT HAVING ANTIMICROBIAL ACTIVITY 2022
  • Maslivets Anna Andreevna
  • Maslivets Andrei Nikolaevich
  • Balandina Svetlana Iurevna
  • Muliukova Alina Borisovna
  • Andreeva Anastasiia Aleksandrovna
  • Poturaev Petr Sergeevich
RU2790482C1
USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYETHYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-EN-2,4,7-TRIONES AS ANTITUBERCULOUS AGENTS 2023
  • Maslivets Andrei Nikolaevich
  • Tretiakov Nikita Alekseevich
  • Balandina Svetlana Iurevna
RU2798423C1
METHOD OF PRODUCING 9-AROYL-8-HYDROXY-6-(2-HYDROXYARYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-2,4,7-TRIONES, HAVING ANTIMICROBIAL ACTIVITY 2021
  • Maslivets Andrej Nikolaevich
  • Balandina Svetlana Yurevna
  • Kobelev Aleksandr Ivanovich
  • Babikova Natalya Vladimirovna
RU2767555C1
USE OF 9-BENZOYL-8-HYDROXY-6-(2-HYDROXYETHYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NONE-2,8-DIEN-4,7-DIONE AS AN ANTIFUNGAL DRUG 2022
  • Maslivets Andrei Nikolaevich
  • Tretiakov Nikita Alekseevich
  • Balandina Svetlana Iurevna
RU2791043C1

RU 2 763 731 C1

Authors

Maslivets Andrej Nikolaevich

Tretyakov Nikita Alekseevich

Balandina Svetlana Yurevna

Dates

2021-12-30Published

2021-06-17Filed