FIELD: chemistry.
SUBSTANCE: invention relates to 2-((3-(4-Bromobenzoyl)-4-hydroxy-1-(2-hydroxyethyl)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)thio) acetic acid
with analgesic activity. The invention also relates to a method for producing said compound, carried out by reacting 8-(4-bromobenzoyl)-3,4-dihydro-1H-pyrrolo[2,1-c][1,4]oxazine-1,6,7-trione with thioglycolic acid in a solvent medium, followed by the isolation of target products.
EFFECT: new compound has been obtained, which can be used as starting products for the synthesis of new heterocyclic systems and in pharmacology as having analgesic activity.
4 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
| APPLICATION OF 3'-(4-BROMOBENZOYL)-4'-HYDROXY-1'-(2-HYDROXYETHYL)SPIRO[BENZO[B][1,4]THIAZINE-2,2'-PYRROLE]-3,5'(1 'H,4H)-DIONE AS AGENT WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
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2019 |
- Tretyakov Nikita Alekseevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Maslivets Anna Andreevna
|
RU2707196C1 |
| APPLICATION OF 3'-AROYL-4'-HYDROXY-1'-(2-HYDROXYETHYL)SPIRO[BENZO[b][1,4]THIAZINE-2,2'-PYRROLE]-3,5'(1'H,4 H)-DIONES AS AGENTS WITH ANALGESIC ACTIVITY |
2021 |
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|
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| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONES AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2813484C1 |
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2021 |
- Maslivets Andrej Nikolaevich
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|
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2023 |
- Maslivets Andrei Nikolaevich
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- Balandina Svetlana Iurevna
|
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| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-IMINO-1-THIA-3,6-DIAZASPIRO[4,4]NON-8-EN-4,7-DIONES AS AGENTS, WITH ANTIMICROBIAL ACTIVITY |
2022 |
- Maslivets Andrei Nikolaevich
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- Balandina Svetlana Iurevna
|
RU2790479C1 |
| 9-AROYL-8-HYDROXY-6-(2-HYDROXYETHYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONS, HAVING ANALGESIC ACTIVITY, AND A METHOD FOR PRODUCTION THEREOF |
2019 |
- Tretyakov Nikita Alekseevich
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- Makhmudov Ramiz Ragibovich
- Maslivets Anna Andreevna
|
RU2707197C1 |
| 3'-AROYL-1-BENZYL-4'-HYDROXY-1'-(2-HYDROXYETHYL)-6,6-DIMETHYL-6,7-DIHYDROSPIRO[INDOLO-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONES POSSESSING ANALGESIC ACTIVITY AND A METHOD FOR THEIR PREPARATION |
2018 |
- Tretyakov Nikita Alekseevich
- Maslivets Andrej Nikolaevich
- Makhmudov Ramiz Ragibovich
- Galeev Andrej Ruslanovich
|
RU2688931C1 |
| APPLICATION OF 1-BENZYL-4'-HYDROXY-1'-(2-HYDROXYETHYL)-3'- (METHOXYBENZOYL)-6,6-DIMETHYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE] 2,4 ,5'(1H,1'H,5H)-TRIONE AS AN AGENT WITH ANTIHYPOXIC ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Makhmudov Ramiz Ragibovich
|
RU2763738C1 |
