FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to the use of individual compounds of class of 3-hydroxy-2,5-dihydro-1H-pyrrol-2-ones as agents having antimicrobial activity, which can also be used as starting products for synthesis of novel heterocyclic systems and in pharmacology.
EFFECT: disclosed is use of 2-((3-(4-methylbenzoyl)-4-hydroxy-1-(2-hydroxyethyl)-5-oxo-2,5-dihydro-1H-pyrrol-2-yl)thio)acetic acid as an agent having antibacterial activity on Staphylococcus aureus, Escherichia coli and antifungal activity on Candida albicans.
1 cl, 1 tbl, 2 ex
| Title |
Year |
Author |
Number |
| USE OF 3-AROYL-4-HYDROXY-1-(2-HYDROXYETHYL)-4'H-SPIRO[PYRROLE-2,5'-[1,2,5]OXADIAZOLO[3,4-b]PYRAZINE]-5,6'(1H,7'H)-DIONES AS AGENTS, HAVING ANTIMICROBIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS |
2024 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2831252C1 |
| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3-DIPHENYL-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONES AGENTS WITH ANTIMICROBIAL ACTIVITY AGAINST S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2813484C1 |
| APPLICATION OF 8-HYDROXY-6-(2-HYDROXYETHYL)-9-(4-METHYLBENZOYL)-2-PHENYL-1-THIA-3,6-DIAZASPIRO[4.4]NON-2,8-DIENE-4,7-DIONE AS AN AGENT WITH ANTIMICROBIAL ACTIVITY AGAINST THE S. AUREUS CULTURE |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2803888C1 |
| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO[4.4]NON-8-ENE-4,7-DIONES AS AGENTS WITH HIGH ANTIMICROBIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS |
2024 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2831126C1 |
| APPLICATION OF 3-(2,4-DIHYDROXY-1-(2-HYDROXYPROPYL)-5-OXO-2-(4-CHLOROPHENYL)-2,5-DIHYDRO-1H-PYRROL-3-YL)QUINOXALIN-2(1H)-ONE AS AN AGENT WITH ANTIMICROBIAL ACTIVITY AGAINST CULTURES OF S. AUREUS AND C. ALBICANS |
2023 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2806037C1 |
| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-IMINO-1-THIA-3,6-DIAZASPIRO[4,4]NON-8-ENE-4,7-DIONES, HAVING HIGH ANTIMICROBIAL ACTIVITY |
2024 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2829454C1 |
| USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-1,3,6-TRIAZASPIRO[4,4]NON-8-ENE-2,4,7-TRIONES AS AGENTS HAVING ANTIMICROBIAL ACTIVITY AGAINST CULTURE OF STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS |
2024 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2828102C1 |
| 2-((3-(4-BROMOBENZOYL)-4-HYDROXY-1-(2-HYDROXYETHYL)-5-OXO-2,5-DIHYDRO-1H-PYRROL-2-YL)THIO) ACETIC ACID WITH ANALGESIC ACTIVITY |
2021 |
- Maslivets Andrej Nikolaevich
- Tretyakov Nikita Alekseevich
- Makhmudov Ramiz Ragibovich
|
RU2763737C1 |
| APPLICATION OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-IMINO-1-THIA-3,6-DIAZASPIRO[4,4]NON-8-EN-4,7-DIONES AS AGENTS, WITH ANTIMICROBIAL ACTIVITY |
2022 |
- Maslivets Andrei Nikolaevich
- Tretiakov Nikita Alekseevich
- Balandina Svetlana Iurevna
|
RU2790479C1 |
| USE OF 4'-HYDROXY-1'-(2-HYDROXYALKYL)-3'-AROYL-6,6-DIMETHYL-6,7-DIHYDROSPIRO[INDOLE-3,2'-PYRROLE]-2,4,5'(1H,1'H,5H)-TRIONS AS AGENTS HAVING BACTERICIDAL ACTION ON BACTERIA STAPHYLOCOCCUS AUREUS |
2024 |
- Tretiakov Nikita Alekseevich
- Maslivets Andrei Nikolaevich
- Balandina Svetlana Iurevna
|
RU2829455C1 |
