Show metadata Hide metadata

(19)

(11)

2 764 807

(13)

(51)

IPC

G01N21/65(2006-01-01)

C12Q1/6806(2018-01-01)

C12Q1/6813(2018-01-01)

C12Q1/6886(2018-01-01)

(21) (22)

Application

2020132737, 2020-10-05

(24)

Start date

2020-10-05

(22)

Actual filing date

2020-10-05

(45)

Published

2022-01-21

(72)

Inventor

Eremina Olga EvgenevnaOgurtsova Anna IvanovnaKapitanova Olesya OlegovnaPisarev Eduard KonstantinovichZatsepin Timofej SergeevichVeselova Irina AnatolevnaZvereva Mariya Emilevna

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Universitet Imeni M.V.Lomonosova»

SET FOR THE DIAGNOSIS OF BLADDER CANCER USING C228T AND C250T MUTATIONS IN THE hTERT GENE PROMOTER AND THE METHOD FOR ITS IMPLEMENTATION Russian patent published in 2022 - IPC G01N21/65 C12Q1/6806 C12Q1/6813 C12Q1/6886

Abstract RU 2764807 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. A set and method for the diagnosis of bladder cancer using C228T and C250T mutations in the promoter of the hTERT gene are proposed. The set includes a sensor and solutions of dye-labeled oligonucleotides with a detection limit of no more than 1 micron, GnuS-C228T-label and GnuS-C250T-label. The method involves taking a biological sample, where one part of the sample is mixed with a solution of the oligonucleotide GnuS-C228T-label, and the other part with a solution of GnuS-C250T-label, carrying out their hybridization, followed by the determination of DNA mutations C228T and C250T.

EFFECT: inventions ensure the achievement of high accuracy in the diagnosis of bladder cancer in the early stages of tumor development.

18 cl, 16 dwg, 2 tbl, 2 ex

Similar patents RU2764807C1

Title	Year	Author	Number
METHOD OF DETECTING AND DETERMINING DNA WITH A GIVEN SEQUENCE USING GIANT RAMAN SCATTERING SPECTROSCOPY	2019	Veselova Irina Anatolevna Eremina Olga Evgenevna Zatsepin Timofej Sergeevich Zvereva Mariya Emilevna Farzan Valentina Mikhajlovna	RU2723160C1
METHOD FOR ANALYSIS OF GENETIC POLYMORPHYSM, DEFINING PREDISPOSITION TO TUMOR DISEASES AND INDIVIDUAL SENSITIVITY TO PHARMACEUTICAL AGENTS BY USING OLYGONUCLEOTIDE BIOLOGICAL MICROARRAY (BIOARRAY)	2005	Zasedatelev Aleksandr Sergeevich Nasedkina Tat'Jana Vasil'Evna Glotov Andrej Sergeevich	RU2303634C2
TEST SYSTEM FOR IDENTIFYING A MUTATION IN THE BTPKD GENE OF THE DOMESTIC DOG (CANIS LUPUS FAMILIARIS), CAUSING POLYCYSTIC KIDNEY DISEASE	2020	Mukij Yuliya Viktorovna Bogomaz Denis Igorevich Pavlova Olga Andreevna Vladimirov Ivan Artemevich	RU2763933C1
METHOD FOR DIAGNOSING VARIANT SOPH c.5741G>A IN NBAS GENE	2024	Zhozhikov Leonid Ruslanovich Vasilev Filipp Filippovich Danilova Anastasiia Lukichna Gurev Anatolii Arsenovich Maksimova Anastasiia Anatolevna Sukhomiasova Aitalina Lukichna Maksimova Nadezhda Romanovna	RU2819985C1
METHOD OF ANALYSIS OF SOMATIC MUTATIONS IN GENES EGFR, KRAS AND BRAF USING LNA-BLOCKING MULTIPLEX PCR AND SUBSEQUENT HYBRIDISATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP)	2014	Emel'Janova Marina Aleksandrovna Nasedkina Tat'Jana Vasil'Evna Ljubchenko Ljudmila Nikolaevna Zasedatelev Aleksandr Sergeevich	RU2552483C1
METHOD FOR ANALYSIS OF SOMATIC MUTATIONS IN GNAQ AND GNA11 GENES USING LNA-BLOCKING MULTIPLEX PCR AND SUBSEQUENT HYBRIDIZATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP)	2017	Emelyanova Marina Aleksandrovna Zasedatelev Aleksandr Sergeevich Nasedkina Tatyana Vasilevna	RU2674687C1
METHOD FOR ANALYSIS OF SOMATIC MUTATIONS IN BRAF, NRAS AND KIT GENES USING LNA-BLOCKING MULTIPLEX PCR AND SUBSEQUENT HYBRIDIZATION WITH OLIGONUCLEOTIDE BIOLOGICAL MICROCHIP (BIOCHIP)	2017	Emelyanova Marina Aleksandrovna Zasedatelev Aleksandr Sergeevich Nasedkina Tatyana Vasilevna	RU2674338C1
KIT FOR DETERMINING CCR5DELTA32 MUTATIONS IN HUMAN GENOME	2020	Dashinimaev Erdem Bairovich Artyukhov Aleksandr Sergeevich Goltsova Aleksandra Sergeevna	RU2748998C1
METHOD FOR SIMULTANEOUS DNA TESTING TO DETECT PRESENCE OF H63D AND C282Y POLYMORPHISMS IN HFE GENE ASSOCIATED WITH GENETIC HEMACHROMATOSIS	2006	Samokhodskaja Larisa Mikhajlovna Tkachuk Vsevolod Arsen'Evich Bochkov Valerij Nikolaevich Balatskij Aleksandr Vladimirovich Makarevich Pavel Igorevich	RU2304170C1
METHOD FOR QUANTITATIVE DETERMINATION OF MUTATIONS F317L AND F359V/C OF THE KINASE DOMAIN BCR-ABL IN PATIENTS WITH CHRONIC MYELOID LEUKEMIA RESISTANT TO THERAPY WITH TYROSINE KINASE INHIBITORS	2019	Tikhonova Vera Vyacheslavovna Kesaeva Laura Arturovna Finashutina Yuliya Pavlovna Misyurin Andrej Vitalevich Semochkin Sergej Vyacheslavovich Kasatkina Nataliya Nikolaevna	RU2698461C1

RU 2 764 807 C1

Authors

Eremina Olga Evgenevna

Ogurtsova Anna Ivanovna

Kapitanova Olesya Olegovna

Pisarev Eduard Konstantinovich

Zatsepin Timofej Sergeevich

Veselova Irina Anatolevna

Zvereva Mariya Emilevna

Dates

2022-01-21—Published

2020-10-05—Filed