FIELD: biotechnology.
SUBSTANCE: invention relates to a method of producing (S)-nicotine by reduction. Said method involves carrying out a process for reducing an alkene compound, represented by formula I, and/or iminium cationic compound represented by formula II, to obtain (S)-nicotine, wherein reduction is carried out using a biocatalytic method or a chiral metal catalyst.
EFFECT: present invention enables to obtain (S)-nicotine, which does not require methylation and provides safety, as well as high output and high purity of the obtained product.
10 cl, 3 dwg, 2 tbl, 11 ex
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