METHOD FOR PRODUCING A SELECTIVE SORBENT FOR SOLID-PHASE EXTRACTION Russian patent published in 2022 - IPC B01J20/30 B01J20/24 B01J20/26 B01D15/26 

FIELD: chemistry.

SUBSTANCE: invention relates to methods for producing selective sorbents for solid-phase extraction and can be used for development of equipment and/or methods for controlling the quality of medicinal products and other objects of analytical control, where chromatographic, optical and other methods for analysis are used. The method for producing a selective sorbent for solid-phase extraction includes the stages of producing a reaction mixture, followed by polymerisation while stirring, wherein a combination of a monomer - ethylcyanoacrylate 1.8 g, hypromellose 0.1 g and template 0.1 g is used to produce the sorbent. Prior to polymerisation, hypromellose is coagulated in the presence of the template at a temperature of 100°C in water, anionic polymerisation of the monomer - ethylcyanoacrylate - is conducted in the presence of the resulting coagulate in a 0.001 M hydrochloric acid solution while stirring. The resulting sorbent is ground, washed with 96.6% ethanol, and dried at room temperature to a constant mass.

EFFECT: increased selectivity of the produced sorbent due to the use of a combination of ethylcyanoacrylate, hypromellose, template in conditions of polymerisation.

1 cl, 2 tbl, 3 ex