METHOD FOR REGISTRATION OF GIANT COMBINATION SCATTERING SPECTRA AND FLOW CELL FOR ITS IMPLEMENTATION Russian patent published in 2022 - IPC G01N21/65 

Abstract RU 2765617 C1

FIELD: optical spectroscopy.

SUBSTANCE: invention relates to the field of optical spectroscopy and relates to a method for recording spectra of giant Raman light scattering. The method includes conjugating molecules of a test sample with magnetic nanoparticles and mixing the resulting conjugates of sample molecules with a buffer for analysis. The method also includes pumping the conjugates of the sample molecules in the buffer through the flow cell, fixing the position of the conjugates of the sample molecules in the cell using a magnetic field, further pumping the buffer for analysis, recording the spectra of giant Raman light scattering in the region of fixing the conjugates of the sample molecules, turning off the magnetic field, pumping assay buffer through the flow cell to deliver the next batch of conjugates of sample molecules or a subsequent sample.

EFFECT: increasing sensitivity and enabling continuous automated analysis of various samples.

11 cl, 2 dwg

.

Similar patents RU2765617C1

Title Year Author Number
METHOD FOR DETECTION OF ENANTIOMERS OF CHIRAL ORGANIC MOLECULES 2021
  • Sokolov Pavel Mikhajlovich
  • Samokhvalov Pavel Sergeevich
RU2780990C1
SUBSTRATE FOR SURFACE REINFORCED RANSCATTERING SPECTROSCOPY 2021
  • Sokolov Pavel Mikhajlovich
  • Samokhvalov Pavel Sergeevich
  • Linkov Pavel Alekseevich
  • Tsoj Tatyana Dmitrievna
  • Nifontova Galina Olegovna
  • Bykov Igor Valentinovich
  • Ivanov Andrej Valerevich
  • Sarychev Andrej Karlovich
  • Bakholdin Nikita Vladimirovich
  • Ryzhikov Ilya Anatolevich
RU2763861C1
METHOD FOR DETERMINING PROTEINS USING GIANT RAMAN SCATTERING USING CRYOSOLS OF PLASMON NANOPARTICLES 2019
  • Durmanov Nikolaj Nikolaevich
  • Eremenko Arkadij Veniaminovich
  • Morgunov Valerij Vasilevich
  • Rykova Valentina Aleksandrovna
  • Evtushenko Evgenij Gennadevich
  • Agafonov Pavel Vladimirovich
  • Kovalev Aleksandr Vasilevich
  • Kurochkin Ilya Nikolaevich
RU2717160C1
METHOD OF DETECTING AND DETERMINING DNA WITH A GIVEN SEQUENCE USING GIANT RAMAN SCATTERING SPECTROSCOPY 2019
  • Veselova Irina Anatolevna
  • Eremina Olga Evgenevna
  • Zatsepin Timofej Sergeevich
  • Zvereva Mariya Emilevna
  • Farzan Valentina Mikhajlovna
RU2723160C1
METHOD OF ANALYSING CYTOCHROME C IN INTACT MITOCHONDRIA BY GIANT COMBINED DIFFUSION SPECTROSCOPY ON NANOSTRUCTURED COATINGS 2014
  • Gudilin Evgenij Alekseevich
  • Semenova Anna Aleksandrovna
  • Brazhe Nadezhda Aleksandrovna
  • Brazhe Aleksej Rudolfovich
  • Maksimov Georgij Vladimirovich
  • Parshina Evgeniya Yurevna
  • Sidorov Aleksandr Vladimirovich
  • Sarycheva Asya Sergeevna
  • Sosnovtseva Olga Vladimirovna
RU2585118C2
METHOD OF DETERMINING METAL IONS IN SOLUTION 2011
  • Panarin Andrej Jur'Evich
  • Terekhov Sergej Nikolaevich
  • Khodasevich Inna Andreevna
RU2460060C1
METHOD FOR DETERMINING SPATIAL STRUCTURE OF BIOMOLECULES 2020
  • Moriachkov Roman Vladimirovich
  • Slatinskaia Olga Vadimovna
  • Shchugoreva Irina Andreevna
  • Zabluda Vladimir Nikolaevich
  • Sokolov Aleksei Eduardovich
RU2751797C1
PLANAR SOLIDPHASE OPTICAL SENSOR FOR DETERMINATION OF PROTEIN COMPOUNDS BY THE METHOD OF SPECTROSCOPY OF GIANT RAMAN SCATTERING AND ITS APPLICATION FOR PROTEIN COMPOUNDS DETECTION 2016
  • Veselova Irina Anatolevna
  • Gudilin Evgenij Alekseevich
  • Sergeeva Elena Andreevna
  • Eremina Olga Evgenevna
  • Semenova Anna Aleksandrovna
  • Sidorov Aleksandr Vladimirovich
  • Shekhovtsova Tatyana Nikolaevna
RU2659987C2
PLANAR NANOSTRUCTURED SENSOR BASED ON SURFACE PLASMON RESONANCE TO ENHANCE RAMAN LIGHT SCATTERING OF HUMAN PLATELETS AND METHOD FOR ITS PRODUCTION 2022
  • Zyubin Andrej Yurevich
  • Rafalskij Vladimir Vitalevich
  • Moiseeva Ekaterina Mikhajlovna
  • Matveeva Karina Igorevna
  • Kon Igor Igorevich
  • Demishkevich Elizaveta Aleksandrovna
  • Kundalevich Anna Anatolevna
  • Evtifeev Denis Olegovich
  • Khankaev Artemij Aleksandrovich
  • Tsibulnikova Anna Vladimirovna
  • Samusev Ilya Gennadevich
  • Bryukhanov Valerij Veniaminovich
RU2788479C1
COMPOSITION HAVING GCR-ACTIVITY FOR DETERMINATION OF POLY-AROMATIC HETEROCYCLIC SULFUR COMPOUNDS IN HYDROCARBON PRODUCTS, PROCESS OF OBTAINING A COMPOSITION, PLANAR SOLID-PHASE OPTICAL SENSOR ON ITS BASIS AND METHOD OF OBTAINING IT, USE OF SENSOR FOR POLY-AROMATIC HETEROCYCLIC SULFUR COMPOUNDS ANALYSIS 2016
  • Volodina Mariya Olegovna
  • Sidorov Aleksandr Vladimirovich
  • Eremina Olga Evgenevna
  • Veselova Irina Anatolevna
  • Gudilin Evgenij Alekseevich
RU2627980C1

RU 2 765 617 C1

Authors

Sokolov Pavel Mikhajlovich

Mochalov Konstantin Evgenevich

Kryukova Irina Sergeevna

Rakovich Yurij Petrovich

Dates

2022-02-01Published

2021-05-25Filed