FIELD: medicine.
SUBSTANCE: invention refers to experimental medicine and clinical pharmacology and aims at studying pharmacokinetic and pharmacodynamic properties of antimicrobial activity of various peptides with molecular weight less than 50 kDa. Method for determining antimicrobial activity of peptides with molecular weight less than 50 kDa in blood serum of experimental animals consists in the fact that the analysed peptide sample is intravenously administered into the body of an experimental animal, blood is sampled at certain intervals to obtain serum, and the obtained serum samples are titrated against St.epidermitis 33 GISK strain.
EFFECT: method enables assessing the pharmacokinetic and pharmacodynamic properties of the drugs intended for treating a bacterial infection.
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Authors
Dates
2022-03-15—Published
2021-04-05—Filed