PHARMACEUTICAL COMPOSITION PRODUCING ANTIOXIDANT, ANTIMICROBIAL, ANTITOXIC HUMAN LACTOFERRIN PROTEIN, METHOD FOR PREPARING IT, AND METHOD OF THERAPY Russian patent published in 2013 - IPC A61K48/00 A61K38/40 C12N15/64 B82Y5/00 A61P39/00 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine, particularly toxicology and radiology, to drug preparations based on antioxidant proteins and methods of using them. The pharmaceutical composition for treating toxic conditions wherein the therapeutic effect is ensured by the action of antioxidant, antimicrobial, antitoxic human lacroferrin protein on the human body contains non-replicating nanoparticles of human adenovirus serotype 5 genome with inserted human lactoferrin expressing human lactoferrin in the therapeutically effective amount in the body, and an expression buffer with the particle content not less than 2.33×10¹¹ of physical particles per ml of the expressing buffer. The method of therapy involves administering the composition in the therapeutically effective dose of 7×10¹¹ of physical particles to 7×10¹³ of physical particles per ml of the expressing buffer per an individual; the composition is administered intravenously.

EFFECT: invention provides the stable therapeutic effect after the single administration of the composition.

17 cl, 14 ex, 4 dwg