FIELD: medicine.
SUBSTANCE: proposed is a computer-implemented method for removing lipid traits with a weak signal. Technical samples without a biological signal and biological samples with a biological signal are obtained. The above samples are compared using a computing apparatus, wherein a threshold of 0.5 is set in a logarithmic scale with a base of two, between the mean values in the technical and biological samples. If at least one lipid trait has a less than 0.5 difference between the mean value in the biological samples and in the technical samples, said lipid trait is removed from the data.
EFFECT: invention reduces the influence of technical factors in the data of liquid chromatography with mass spectrometry by removing lipid traits with a weak signal.
1 cl, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR IMPROVING QUALITY OF ANNOTATION OF LIPID FEATURES RELATING TO INDIVIDUAL LIPID CLASSES USING INFORMATION ON DELAY TIME IN MASS SPECTROMETER | 2020 |
|
RU2743418C1 |
| METHOD AND SYSTEM FOR CORRECTING UNDESIRABLE BATCH EFFECTS IN MICROBIOME DATA | 2019 |
|
RU2742003C1 |
| METHOD FOR DETECTING DIABETIC FETOPATHY | 2020 |
|
RU2742801C1 |
| METHOD OF PROCESSING CHROMATO-MASS-SPECTROMETRIC DATA TO INCREASE THE EFFICIENCY OF SEARCH FOR DIAGNOSTIC MARKERS IN CLINICAL STUDIES | 2021 |
|
RU2803128C2 |
| METHOD FOR DETECTING TYPE 1 DIABETES MELLITUS | 2020 |
|
RU2752372C1 |
| METHOD FOR DIAGNOSING MENTAL DISORDERS BY BLOOD LIPIDS | 2022 |
|
RU2818128C2 |
| SYPHILIS DIAGNOSTIC TECHNIQUE WITH USING METHOD OF DIRECT PROTEOMIC BLOOD SERUM PROFILING | 2008 |
|
RU2381505C1 |
| DIAGNOSTIC TECHNIQUE FOR PREECLAMPSIA BY AMINO ACID PROFILE OF BLOOD PLASMA | 2019 |
|
RU2717942C1 |
| NEW APPLICATION OF PROBIOTICS | 2009 |
|
RU2497536C2 |
| METHOD FOR DIFFERENTIAL DIAGNOSTICS OF DIABETES MELLITUS TYPE | 2021 |
|
RU2788106C1 |
