FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to obstetrics, and can be used to diagnose subclinical intrauterine infection (IUI) in the second trimester of pregnancy. With a total of three out of five points on the IUI criteria scale: burdened obstetric and gynecological history: chronic endometritis, non-developing pregnancy, induced abortion, spontaneous miscarriages, premature birth - 1 point; cervicitis - 1 point; persistent threat of abortion - 1 point; violation of utero-fetal blood flow - 1 point; changes in the fetoplacental complex during ultrasound examination: structural changes in the placenta, an abnormal amount of water - 1 point, and the level of matrix metalloproteinase MMP-8 more than 17 ng/ml in the cervical mucus in the patient is diagnosed with subclinical IUI.
EFFECT: method enables non-invasive diagnosis of subclinical intrauterine infection in the second trimester of pregnancy by determining MMP-8 in cervical mucus in women in the second trimester of pregnancy, which improves the accuracy of diagnosis of subclinical intrauterine infection, determines the amount of therapeutic measures.
1 cl, 1 ex
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