METHOD FOR PREDICTION OF PRESENCE OF INTRAAMNIOTIC INFLAMMATION IN ISTHMIC-CERVICAL INSUFFICIENCY Russian patent published in 2025 - IPC G01N33/68 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to obstetrics and gynaecology, and can be used for the prediction of intraamniotic inflammation accompanying isthmic-cervical insufficiency (ICI). Cervical fluid is sampled from a pregnant woman diagnosed with ICI, the concentration of type 6 interleukin (IL-6) is determined, which is used to predict the presence of intraamniotic inflammation: microbe-associated and aseptic form. If the cervical fluid IL-6 value is 8.0 pg/ml or less, a low risk of intraamniotic inflammation is predicted. If the cervical fluid IL-6 level is 11.1 pg/ml or more, a high risk of intraamniotic inflammation is predicted. If the cervical fluid IL-6 concentration is 8.1 to 11.0 pg/ml, a moderate risk of intraamniotic inflammation is predicted.

EFFECT: method provides an opportunity to increase the accuracy of predicting the risk of intraamniotic inflammation, especially its aseptic form, in patients with ICI due to the determination of IL-6 in cervical fluid taken during a standard gynaecological examination of the cervix in the mirrors.

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