METHOD FOR MODELING DELIMITED ACUTE PURULENT MASTITIS IN THE EXPERIMENT Russian patent published in 2022 - IPC G09B23/28 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to experimental and purulent surgery. The modeling method consists in introducing the pathogen of the pathological process into the subcutaneous space of the rabbit mammary gland by forming a cavity by inserting a transcutaneously modified Foley catheter with a balloon at the distal end. The balloon surface is preliminarily infected with a suspension of staphylococcus and Escherichia coli with a microbial load of 5×105 CFU/ml. The balloon is filled with physiological sodium chloride solution in a volume of 2 ml. Then, dressing and fixation of the distal part of the catheter is carried out using skin duplication. In this state, the balloon is left in the resulting cavity for five days, after which the catheter is emptied and removed. The method allows to reduce the number of manipulations, bypassing the additional time spent on the formation of the first aseptic cavity.

EFFECT: invention eliminates the early death of rabbits by reducing the time of formation of a purulent process and minimal trauma to surrounding tissues, which gives time to develop new methods for the effective treatment of acute purulent mastitis.

1 cl, 1 ex, 4 dwg