COMPOSITIONS AND METHODS FOR PAIN RELIEF Russian patent published in 2022 - IPC C07C311/19 C07C311/51 C07D213/75 C07D295/13 C07D295/192 A61K31/16 A61K31/40 A61K31/44 A61K31/495 A61K31/5375 A61P29/00 

Abstract RU 2777368 C2

FIELD: organic chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely to a compound of the formula (I), where R includes NH2, N(CH3)2, NHCH3, N(CH2CH3)2, NH(CH2)2C6H5, NHCH2C6H5, NHCH2CH2CH2CH3, NHCH2C6H4OCH3, NHCH2C6H3Cl2, NHCH2C6H4CH3, NHCH2C6H4Cl, NHCH2C6H4NO2, NH-cyclopentyl, NHCH2CH(CH3)2, NHCH(CH3)2, NHCH2CH2C6H3(OH)2, NHCH2CH2-pyrrolidinyl, N(CH3)CH2CH2OH, NHCH2CH(OH)CH2NH2; or its pharmaceutically acceptable salt. The invention also relates to a compound of the formula (II), values of radicals are specified in the claims, to a method for relief or prevention of visceral and nociceptive pain.

EFFECT: effective pain relief by a derivative of the general formula (I) and (II).

(I)

(II)

20 cl, 11 dwg, 3 tbl, 1 ex

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RU 2 777 368 C2

Authors

Bazan Nikolas

Bazan Ernan

Alvares-Bujlya Khulio

Pol Dennis

Burgos Karolina

Dates

2022-08-02Published

2018-03-12Filed