FIELD: medicine; oncology.
SUBSTANCE: invention relates to medicine, namely to oncology; it can be used for enhancing tumor cell death. A method includes impact with a drug 1 hour before radiation and radiation of bowel cancer cells with HCT116 dose of 4 Gr. An inhibitor of cyclin-dependent kinases CDK 8/19 Senexin B is used as the drug.
EFFECT: use of the invention allows for the reduction in survivability of tumor cells due to the action of a combination on their survival mechanism and prevention of the formation of resistance under the action of gamma-radiation.
2 cl, 2 ex, 3 dwg
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Authors
Dates
2022-08-11—Published
2020-09-23—Filed