FIELD: medicine.
SUBSTANCE: group of inventions refers to medicine and can be used to treating pancreatic cancer with certain ATR inhibitors to a patient in combination with other types of antitumor therapy such as gemcitabine therapy, radiation therapy or gemcitabine and radiation therapy together. A method for increasing the sensitivity of pancreatic cancer cells to chemoradiotherapy, the use of an ATR inhibitor in the manufacture of a medicament for the pancreatic cancer treatment and for enhancing the sensitivity of pancreatic cells to chemoradiotherapy are also provided.
EFFECT: group of inventions provides treatment for pancreatic cancer in a patient by administering to the patient ATR inhibitor (VE-822) in combination with other types of antitumor therapy.
14 cl, 21 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF TREATING CANCER USING A COMBINATION OF CHK1 AND ATR INHIBITORS | 2015 |
|
RU2736219C2 |
| TREATING CANCER WITH COMBINATION OF RADIATION THERAPY, CERIUM OXIDE NANOPARTICLES AND CHEMOTHERAPEUTIC AGENT | 2015 |
|
RU2704811C2 |
| SYNERGETIC PHARMACEUTICAL COMBINATION FOR CANCER TREATMENT | 2007 |
|
RU2438664C2 |
| METHOD FOR APPLYING COMBINED ANTITUMOR THERAPY INCLUDING SUBSTITUTED ACRYLOYL DISTACMYCIN DERIVATIVES USAGE AND RADIATION THERAPY | 2003 |
|
RU2314807C2 |
| METHOD OF TREATING RECURRENT NON-SMALL CELL LUNG CANCER | 2014 |
|
RU2558473C1 |
| PHARMACEUTICAL COMBINATION FOR CANCER TREATMENT | 2018 |
|
RU2801665C2 |
| METHOD OF TREATING CANCER USING A COMBINATION OF DNA DAMAGING AGENTS AND ATR INHIBITORS | 2016 |
|
RU2768621C1 |
| COMBINED THERAPY FOR CANCER TREATMENT | 2015 |
|
RU2708374C2 |
| METHOD OF TREATING CANCER (VERSIONS) | 2006 |
|
RU2447889C2 |
| ANTIBODIES AGAINST PD-1 FOR TREATMENT OF LUNG CANCER | 2018 |
|
RU2771759C2 |
Authors
Dates
2018-03-26—Published
2012-10-01—Filed