METHOD FOR PRODUCTION OF OXASPIROCYCLIC DERIVATIVE AND ITS INTERMEDIATE COMPOUND Russian patent published in 2022 - IPC C07D311/96 C07D405/04 C07D409/14 

Abstract RU 2777983 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method for the production of an oxaspirocyclic derivative represented by the formula I, where R1 is hydrogen; R2 is optionally substituted tetrahydronaphthyl or thienyl, a substitute is -OR3; n is equal to 0 or 1; R are such as defined in cl. 1; R3 is C1-6 alkyl. The invention also relates to intermediate compounds (D1), (C) and their production methods.

EFFECT: new method for the production of a compound of the formula (I) with improved yield is developed, which is suitable for industrial large-scale production.

25 cl

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RU 2 777 983 C2

Authors

Li, Wenhai

Qi, Weixing

Qiu, Zhenjun

Dates

2022-08-12Published

2018-09-27Filed