METHOD FOR EARLY DETECTION OF NEUROLOGICAL DISORDERS IN PATIENTS WITH COVID-19 Russian patent published in 2022 - IPC A61B5/02 A61B3/13 A61B5/11 A61B18/20 G16H10/20 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to infectious diseases, and can be used for early detection of neurological disorders in patients who have undergone COVID-19. Three validated questionnaires COMPASS-31, DN4, the FM-Q Fibromyalgia Questionnaire and the Beighton Joint Hypermobility Assessment are used. An active orthostatic test and confocal microscopy of the cornea are performed. With a combination of values ​​of more than 50 points according to the COMPASS-31, DN4, FM-Q questionnaires and assessment of joint hypermobility according to the Bayton scale, in combination with an increase in heart rate after verticalization by 30 or more beats in 2 consecutive measurements and the following indicators of early neurological disorders during confocal microscopy of the cornea: the number of main nerve fibers is 2±0.96 or less, the nerve branching is 9.52±5.11 or more, the tortuosity coefficient of nerve fibers is 17.31±4.76 or more, the number of Langerhans cells is 30±2.56 determine the initial degree of manifestation of neurological disorders in patients who have undergone COVID-19.

EFFECT: method enables early detection of neurological disorders in post-COVID-19 patients by using three validated questionnaires COMPASS-31, DN4, FM-Q, assessing joint hypermobility using the Bayton scale, performing an active orthostatic test and confocal microscopy of the cornea.

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