FIELD: biotechnology.
SUBSTANCE: method for isolation of sialic acid from fermentation broth is proposed. The method includes a stage of removal of biomass from fermentation broth. Then, the resulting clarified solution is subjected to treatment on a cation-exchanger and treatment on an anion-exchanger under conditions, at which sialic acid passes through ion-exchange material and is present in a passing flow. Then, a stage of removal of salts by electrodialysis is carried out.
EFFECT: invention allows for obtaining sialic acid with a high degree of purity, with quality suitable for use in the food industry, and on an industrial scale during one cycle.
15 cl, 8 dwg, 3 tbl, 7 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PURIFICATION OF L-FUCOSE FROM FERMENTATION BROTH | 2018 |
|
RU2789351C2 |
| SPRAY-DRIED SIALYLLACTOSE | 2018 |
|
RU2802680C2 |
| SPRAY DRIED TETRASACCHARIDES | 2018 |
|
RU2812853C2 |
| SPRAY DRIED LACTO-N-FUCOPENTAOSE | 2018 |
|
RU2812864C2 |
| SPRAY-DRIED BREAST MILK OLIGOSACCHARIDE MIXTURE | 2018 |
|
RU2803849C2 |
| SPRAY DRIED 3-FUCOSYLLACTOSE | 2018 |
|
RU2810298C2 |
| METHOD OF PURIFYING SIALYLATED OLIGOSACCHARIDES | 2018 |
|
RU2799091C2 |
| PURIFICATION OF OLIGOSACCHARIDES FROM FERMENTATION BROTH BY FILTRATION | 2020 |
|
RU2808729C2 |
| METHOD FOR DRYING BREAST MILK OLIGOSACCHARIDES | 2020 |
|
RU2805178C1 |
| SIMPLE METHOD OF SIALILLACTOSE PURIFICATION | 2019 |
|
RU2793469C2 |
