FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to psychiatry, neurology and pediatrics. A method for predicting the severity of the course of autism spectrum disorders in children is proposed, including the study of blood serum to determine the concentration of the prognostic biomarker neurotrophin BDNF. With a decrease in the level of BDNF concentration in the blood serum less than 525.38 pg/ml, a high risk of developing neurodysfunction, proapoptotic processes and the formation of a severe form of autism are diagnosed.
EFFECT: invention provides an extension of the arsenal of means for making a diagnosis at the early stages of the development of a disease and the possibility of monitoring the effectiveness of prescribed therapeutic measures.
1 cl, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR REHABILITATION OF CHILDREN WITH AUTISM SPECTRUM DISORDER | 2022 |
|
RU2788892C1 |
| METHOD OF DIFFERENTIAL DIAGNOSIS OF CHILDHOOD AUTISM OF MILD SEVERITY, ATYPICAL AUTISM AND SCHIZOPHRENIA IN CHILDREN | 2022 |
|
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| METHOD OF DETERMINING THE NECESSITY OF USING PSYCHO PHARMACOTHERAPY AMONG THE PATIENTS WITH DISORDERS OF AUTIST SPECTRUM AT THE MOMENT OF THEIR EXAMINATION | 2017 |
|
RU2643760C1 |
| MODULATION sAPP, sAPPα AND BDNF LEVELS IN INDIVIDUALS DIAGNOSED WITH FXS AND ASD | 2013 |
|
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| USING ACAMPROSATE FOR MODULATING ACTIVATION OF ERK1/2 IN ANIMAL MODELS FXS AND ASD AND PEOPLE DIAGNOSED WITH FXS AND ASD | 2014 |
|
RU2696481C2 |
| METHOD FOR PREDICTION OF INFANTILE CEREBRAL PARALYSIS IN PREMATURE NEWBORNS WITH EXTREMELY LOW BIRTH WEIGHT | 2014 |
|
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| METHOD FOR PREDICTION OF THE RISK OF DEVELOPING SEVERE COMPLICATIONS OF PREECLAMPSIA | 2020 |
|
RU2741730C1 |
| METHOD FOR PREDICTION OF CLINICAL COURSE OF HYPOXIC-ISCHEMIC CENTRAL NERVOUS SYSTEM INJURY IN INFANTS | 2012 |
|
RU2487360C1 |
| METHOD FOR DIFFERENTIAL DIAGNOSIS OF CHILD SCHIZOPHRENIA AND CHILD AUTISM BY NUMBER OF COPIES OF GENES CODING RIBOSOMAL RNA IN GENOME OF CHILD WITH MENTAL DISORDERS | 2023 |
|
RU2816043C1 |
| METHOD OF PREDICTING FORMATION OF OCCLUSIVE POST-HAEMORRHAGIC HYDROCEPHALUS IN PREMATURE BABIES WITH EXTREMELY LOW BODY WEIGHT AT BIRTH | 2014 |
|
RU2554781C1 |
