PANEL FOR DETERMINING PREDISPOSITION TO THE DEVELOPMENT OF DISORDERS OF THE FUNCTIONING OF THE THYROID SYSTEM AND ITS USE Russian patent published in 2022 - IPC C12Q1/6827 C12Q1/6883 

FIELD: medical biotechnology.

SUBSTANCE: invention relates to the field of medical biotechnology, specifically to the diagnosis of predisposition to the development of thyroid disorders by identifying gene polymorphisms, and can be used to determine the likelihood of developing functional disorders of the thyroid system, etiologically caused by various polymorphic variants in the genes responsible for the activity of enzymes that are involved in biosynthesis, intracellular action and utilization of thyroid hormones. Proposed panel based on a unique combination genotype polymorphisms of the DIO1, DIO2, TPO, TSHR and TG genes, its use and method for detecting susceptibility to thyroid disorders, such as hyper- or hypothyroidism.

EFFECT: proposed inventions make it possible to simultaneously identify the most common polymorphisms, which makes it possible to carry out a more complete diagnostic coverage and not miss possible changes in the genotype.

3 cl, 2 tbl, 13 ex