METHOD FOR DIAGNOSING EPIDEMIC PAROTITIS Russian patent published in 2022 - IPC A61B1/00 G01N33/535 G01N33/493 

Abstract RU 2785486 C1

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely, to paediatrics and infectious diseases. Anamnestic data is collected from the patient with suspected parotid infection in order to determine asthenic syndrome. An objective examination and palpation of the parotid region are performed in order to detect signs of bilateral inflammation of the salivary glands; the oral cavity is examined in order to identify mucosal dryness; the level of diastase is determined in urine by the kinetic colorimetric method. Each of the determined indicators is assigned a score indicating the presence of a symptom (1 point) or the absence thereof (0 points). The probability of the presence of epidemic parotitis is then calculated using the logistic regression equation described by the formula

wherein p is the probability of presence of epidemic parotitis, %; e is the base of a natural logarithm, equal to 2.7; K is the constant of the logistic regression equation, equal to 5.65; a is the presence or absence of asthenic syndrome in the patient; b is the presence or absence of bilateral inflammation of the parotid salivary glands in the patient; c is the presence or absence of mucosal dryness in the patient; d is the presence or absence of a high level of diastase in the urine of the patient relative to the physiological norm. If the value of p is equal to or greater than 50%, the presence of epidemic parotitis in the patient is diagnosed. If p is less than 50%, the diagnosis of epidemic parotitis is ruled out.

EFFECT: possibility of improving the accuracy and quality of diagnosing epidemic parotitis in the shortest time, availability of the method for research during the initial examination by a paediatrician or an infectious disease specialist in clinical practice, ease of implementation thereof with a high sensitivity and specificity.

1 cl, 3 ex

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RU 2 785 486 C1

Authors

Sofronova Lyudmila Vasilevna

Postanogova Nina Olegovna

Vorobeva Natalya Nikolaevna

Okishev Mikhail Anatolevich

Semerikov Vadislav Vasilevich

Dates

2022-12-08Published

2022-09-26Filed