APPARATUS FOR CONTINUOUS MULTI-PARAMETER MONITORING OF THE PHYSICOCHEMICAL CHARACTERISTICS OF BIOLOGICAL SUSPENSIONS Russian patent published in 2022 - IPC G01N21/01 

FIELD: chemistry.

SUBSTANCE: invention relates to the field of analytical chemistry, namely, to the field of means of determining the state of energy, concentrations of dissolved oxygen, free calcium, membrane potential on the membranes of organelles and cells, and the osmotic volume and other parameters thereof in aqueous suspensions of biological objects, and can be used in various fields of medical and biological research. Apparatus for continuous multi-parameter monitoring of the physicochemical characteristics of biological suspensions is characterised by the fact containing a body, located wherein are a cell with at least six measuring channels made for determining the parameters of the biological suspensions based on the measured optical characteristics, wherein one of the channels is intended for measuring oxygen; a power source; a magnetic mixer located in the cell; a heater for the tested substance and a temperature sensor, located in the cell; an electronic control board; five optical emission sources installed in the measuring channels and five optical emission recorders also installed in the measuring channels, wherein the optical radiation recorders are connected to the inputs of the amplifier and analogue-to-digital converter unit, the output whereof is connected to the input of the recording apparatus, wherein at least the oxygen sensor constitutes an assembly containing at least one Y-shaped fibre cord with a composite core, composed of two physically mixed fibre bundles intended for separating the optical paths of excitation and recording of the optical signal, wherein arranged consecutively against the end of the first fibre bundle of the Y-shaped fibre cord are an excitation emission emitter and a light filter, arranged consecutively against the end of the second fibre bundle of the Y-shaped fibre cord are a light filter and a photodetector, an attachment for placing the test sample is located opposite the common end of the fibre cord, and a power source is connected to all power-consuming elements of the apparatus.

EFFECT: increase in the number of characteristics collected simultaneously from a single sample, reduced test time.

6 cl, 1 tbl