FIELD: medicine.
SUBSTANCE: invention relates to medicine, and can be used in the local treatment of skin wounds in order to fill the wound defect for further replacement with the body's own tissue and stimulate its regeneration. A biodegradable 3D matrix for healing skin defects based on composite polycaprolactone, manufactured by printing on a 3D printer, has a specified spatial organization of 90° along the x, y, z axes with the formation of microcells, which together make up a three-dimensional cellular grid with a cell side of 1, 5 mm, filament diameter 0.3 mm, layer height when printed is 0.05 mm.
EFFECT: invention provides optimal shape parameters of a 3D skin matrix for healing damage to skin tissue, ensuring the safety of its use.
2 cl, 3 dwg, 1 tbl, 1 ex
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Authors
Dates
2022-12-21—Published
2022-04-05—Filed