Show metadata Hide metadata

(19)

(11)

2 786 864

(13)

(51)

IPC

C07D207/16(2006-01-01)

C07D207/14(2006-01-01)

C07D403/06(2006-01-01)

C07D403/14(2006-01-01)

A61K31/5377(2006-01-01)

A61P3/04(2006-01-01)

A61P3/10(2006-01-01)

A61P15/10(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2021137235, 2020-11-06

(24)

Start date

2020-11-06

(22)

Actual filing date

2020-11-06

(45)

Published

2022-12-26

(72)

Inventor

Kang, Seung WanPark, Hee DongPark, Hee DongYeo, Su JinPark, Hyun SeoHong, Ji HoAhn, Hye WonChoi, Eun Sil

(73)

Holder

Lg Chem, Ltd.

MELANOCORTIN-4 RECEPTOR AGONISTS Russian patent published in 2022 - IPC C07D207/16 C07D207/14 C07D403/06 C07D403/14 A61K31/5377 A61P3/04 A61P3/10 A61P15/10 A61P29/00

Abstract RU 2786864 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely to a compound of formula 1 or its pharmaceutically acceptable salt, where R1 is a C₂-C₅ alkyl. The invention also relates to a pharmaceutical composition based on a compound of formula 1, its use for the preparation of a drug and to a method for the treatment or prevention of these diseases.

EFFECT: excellent agonistic activity against melanocortin receptors, manifested by the formula 1 compound, which can be used to prevent or treat obesity, diabetes, inflammation and erectile dysfunction.

Formula 1

19 cl, 10 tbl, 16 ex

Similar patents RU2786864C1

Title	Year	Author	Number
MELANOCORTIN RECEPTOR AGONISTS	2007	Choi Sung Pil Akhn In Ae Li Sang Khjup Li Sang Dae Shin Mi Sook Li Koo Choj Deog Jang Shim Dong Sup Jim Khieon Dzoo Joon Min Kiung Chung Soo Jong Li Dzung Ae Kha Jong Khva Kim Jang Kvan Park Oeuk Li Khiun Min Kim Joun Khoa	RU2411240C2
BENZYLPHENYLCYCLOHEXANE DERIVATIVES AND METHODS OF THEREOF APPLICATION	2008	Chehn' Juan'Vehj Pehn Kun' Chzhan Lili Lv Binkhua Sjuj Bajkhua Dong Tszjatszja Du Tszijuan' Fehn Jan' Sjuj Geh Rajjappan Vasantakumar Sid Brajan	RU2505521C2
PIPERAZINE DERIVATIVE	2016	Sugane, Takashi Makino, Takuya Yamashita, Daisuke Yonetoku, Yasuhiro Tanabe, Daisuke Mihara, Hisashi Asai, Norio Osoda, Kazuhiko Shimizu, Takafumi Moritomo, Hiroyuki Sugasawa, Keizo Maeno, Kyoichi Hosogai, Naomi	RU2731913C2
SHIP1 MODULATORS AND METHODS RELATED THERETO	2014	Makkenzi Llojd F. Makruri Tomas B. Kharvig Kertis Bogutski Devid Rejmond Dzheffri R. Pettigryu Dzheremi D.	RU2679805C2
PRODRUG OF FLUORINE-CONTAINING AMINO ACID	2013	Khasikhayata Takasi Otake Norikadzu Miyakosi Naoki Sakagami Kazunari	RU2639868C1
NOVEL AMIDE DERIVATIVE FOR INHIBITING GROWTH OF CANCER CELLS	2008	Li Kvang-Ok Cha Mi Joung Kim Mi Ra Dzung Joung Khee Li Chang Gon Kim Se Joung Bang Keukchan Park Bum Voo Choi Bo Im Chae Jun Dzung Ko Mi Joung Kim Khan Kiong Akhn Joung-Gil Kim Maeng Sup Li Gvan Sun	RU2434010C2
LIGAND CONJUGATE WITH CYTOTOXIC DRUG PREPARATION, METHOD AND APPLICATION THEREOF	2016	Syuj Tszyanyan Chzhan In Tsyuj Bolej Chzhan Fuyao Yuj Syuchzhao Lian Tszindun Tszyan Gujyan Chzhan Lyanshan Li An Van Yali	RU2708461C2
NEW BIPHENYL COMPOUND OR ITS SALT	2018	Yamashita, Satoshi Ogawa, Takahiro	RU2765152C2
AMINOPYRIMIDINE DERIVATIVES AND USE THEREOF AS AROMATIC HYDROCARBON RECEPTOR MODULATORS	2021	Park, Jung-Sang Cha, Daewon Lee, Wonhyung Joo, Min Sung Yoon, Taeyoung Doh, Hyounmie Sung, Hyun Jung Lee, Bo Ryeong Song, Seunghyun Kim, Yoonjung Choi, Ji Hoon Jung, Hyeon Seok	RU2826628C1
FIBROBLAST GROWTH FACTOR RECEPTOR INHIBITORS	2014	Bifalko Nil Dipetro Lusian V. Khodaus Brajan L. Miduturu Chandrasekkhar V.	RU2704112C2

RU 2 786 864 C1

Authors

Kang, Seung Wan

Park, Hee Dong

Yeo, Su Jin

Park, Hyun Seo

Hong, Ji Ho

Ahn, Hye Won

Choi, Eun Sil

Dates

2022-12-26—Published

2020-11-06—Filed