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(19)

(11)

2 786 864

(13)

(51)

IPC

C07D207/16(2006-01-01)

C07D207/14(2006-01-01)

C07D403/06(2006-01-01)

C07D403/14(2006-01-01)

A61K31/5377(2006-01-01)

A61P3/04(2006-01-01)

A61P3/10(2006-01-01)

A61P15/10(2006-01-01)

A61P29/00(2006-01-01)

(21) (22)

Application

2021137235, 2020-11-06

(24)

Start date

2020-11-06

(22)

Actual filing date

2020-11-06

(45)

Published

2022-12-26

(72)

Inventor

Kang, Seung WanPark, Hee DongPark, Hee DongYeo, Su JinPark, Hyun SeoHong, Ji HoAhn, Hye WonChoi, Eun Sil

(73)

Holder

Lg Chem, Ltd.

MELANOCORTIN-4 RECEPTOR AGONISTS Russian patent published in 2022 - IPC C07D207/16 C07D207/14 C07D403/06 C07D403/14 A61K31/5377 A61P3/04 A61P3/10 A61P15/10 A61P29/00

Abstract RU 2786864 C1

FIELD: organic chemistry.

SUBSTANCE: invention relates to the field of organic chemistry, namely to a compound of formula 1 or its pharmaceutically acceptable salt, where R1 is a C₂-C₅ alkyl. The invention also relates to a pharmaceutical composition based on a compound of formula 1, its use for the preparation of a drug and to a method for the treatment or prevention of these diseases.

EFFECT: excellent agonistic activity against melanocortin receptors, manifested by the formula 1 compound, which can be used to prevent or treat obesity, diabetes, inflammation and erectile dysfunction.

Formula 1

19 cl, 10 tbl, 16 ex

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RU 2 786 864 C1

Authors

Kang, Seung Wan

Park, Hee Dong

Yeo, Su Jin

Park, Hyun Seo

Hong, Ji Ho

Ahn, Hye Won

Choi, Eun Sil

Dates

2022-12-26—Published

2020-11-06—Filed