METHOD FOR ASSESSING THE THROMBOLYTIC POTENTIAL OF MICROMYCETES Russian patent published in 2023 - IPC C12Q1/37 C12N9/50 C12N1/14 

Abstract RU 2788697 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. A method for assessing the thrombolytic potential of a micromycete is proposed, which includes determining in a sample of its culture fluid the indicators of the degree of thrombolysis, the presence of fibrinolytic activity and plasminogen activator activity, the temperature optimum and the pH optimum, followed by the calculation of the coefficient of thrombolytic potential of TP according to the presented formula, followed by ranking the coefficient thrombolytic potential of TP for the studied micromycete: with TP < 8 - low thrombolytic potential of the studied micromycete; at 8 ≤ TP ≤ 12 - average thrombolytic potential of the studied micromycete; at TP> 12 - high thrombolytic potential of the studied micromycete.

EFFECT: invention provides an extension of the arsenal of methods for identifying promising producers of thrombolytic enzymes among the variety of existing strains of micromycetes.

1 cl, 4 dwg, 3 tbl, 3 ex

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RU 2 788 697 C2

Authors

Fokichev Nikolai Sergeevich

Osmolovskii Aleksandr Andreevich

Lukianova Anna Aleksandrovna

Kornienko Elena Igorevna

Nalobin Denis Sergeevich

Dates

2023-01-24Published

2020-07-10Filed