FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to cardiology, and can be used to determine the risk of progression of atherosclerosis in a patient with coronary heart disease (CHD). The risk of rapidly progressive atherosclerosis is determined, for which the patient's age is determined (X1), the presence or absence of carotid artery stenosis by 50% or more of the lumen of the vessel on at least one side (X2), the presence or absence of obesity by body mass index (X3) , the presence or absence of stable angina pectoris in history (X4), the patient's serum concentrations of highly sensitive C-reactive protein (hsCRP) (X5) and high-density lipoprotein cholesterol (HDL-C) (X6) are determined. The above parameters are given the following values: X1 is indicated as the number of completed years of the patient at the time of assessment; X2 is indicated equal to 1 if the patient has stenosis of the carotid arteries by 50% or more of the lumen of the vessel on at least one side and equal to 0 if the stenosis of the carotid arteries is less than 50% of the lumen of the vessel; X3 is indicated equal to 1 if the patient has obesity of more than 1 degree, in the absence of obesity of more than 1 degree - equal to 0; X4 is indicated equal to 1 in the presence of stable angina pectoris in history, in its absence - equal to 0; X5 is indicated in mg/l; X6 is indicated in mM/l. The values X1- X6 are substituted into the formula:
With a value 
equal to or greater than 0.4, the risk of rapidly progressive atherosclerosis in a patient is predicted. If the value is less than 0.4, a spontaneous course of atherosclerosis is predicted.
EFFECT: method provides the possibility of identifying patients with coronary artery disease at risk of rapidly progressive atherosclerosis, accessibility, ease of use through the use of parameters determined within the framework of federal standards for managing patients with CHD.
1 cl, 2 tbl, 1 ex
