FIELD: biotechnology.
SUBSTANCE: invention relates to heteroaromatic compounds. A compound of the formula (I) is proposed, where R1 is -C(O)OR15 or -C(O)NR10R11; R2 is H, halogen, C1-6alkyl, or C1-6halogenalkyl; R3 is
A is selected from C(H), Y is selected from -CH2-; R4 is halogen or C2-9heterocycloalkyl optionally substituted with 1 or 2 R14; R5 is H, halogen, C1-6alkyl, C1-6halogenalkyl, C1-6halogenalkoxy, or phenyl; R6 is hydrogen, halogen, or C1-6alkyl; R10 and R11 are independently selected from H or C1-6alkyl; R12 is H, halogen, or C1-6alkyl; R13 is H or C1-6alkyl; n and m are equal to 0 or 1; p and q are equal to 0, 1, or 2. Specific compounds, a pharmaceutical composition, a method for elimination of pain, and a method for the treatment of migraine are also proposed.
EFFECT: obtainment of new monoacylglycerol lipase (MAGL) modulators.
17 cl, 38 ex, 2 tbl
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