METHOD FOR TREATMENT OF A FLAT FORM OF ORAL LEUKOPLAKIA IN PATIENTS USING FIXED ORTHODONTIC APPLIANCES Russian patent published in 2023 - IPC A61N5/67 A61K8/65 A61K38/39 A61K41/00 A61P31/02 A61P1/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to dentistry. The Photoditazin photosensitizer is applied to a lesion for 15 minutes, then photodynamic therapy is carried out with the Lakhta-Milon-662/0.6 instrument at a wavelength of 662 nm and a light irradiation power of 0.6 W in continuous mode using a light guide with a lens for external irradiation contact method for 15-20 minutes. Then the photosensitizer is washed with distilled water, and the Emalan collagen hydrogel is applied. The procedure is carried out 3 times with a week interval. Furthermore, the patient independently applies the Emalan collagen hydrogel in a 1-2 mm thick layer 2 times a day for 3 weeks.

EFFECT: use of the invention provides an extension of the remission period up to 18 months, increase in the therapeutic effect due to the impact on the main links of the disease pathogenesis, which is manifested in improving the clinical findings, normalizing the local immunity of the oral cavity and stabilizing the free radical oxidation of the oral fluid, reducing the method invasiveness.

1 cl, 2 ex