PREPARATION METHOD OF NITRO COMPOUND AND QUINOXALINE COMPOUND Russian patent published in 2023 - IPC C07B61/00 C07C209/68 C07C211/56 C07C213/08 C07C217/92 C07D241/44 

FIELD: chemistry.

SUBSTANCE: invention relates to the preparation method of a compound with formula (3) which is suitable as an intermediate for the production of physiologically active organic compounds such as agrochemicals, drugs, etc. The method includes reacting a compound with formula (1) with a compound with formula (2) using a tertiary alcohol and a base. The base is a compound selected from alkali metal hydrides and alkali metal amides, or a plurality of compounds including a base containing lithium as the first compound and a second compound selected from alkali metal hydrides, alkali metal amides, alkoxides, alkyl metals, alkali metals and organic bases. The reaction is carried out in the presence of a solvent, where the solvent contains toluene, xylene, chlorobenzene, dichlorobenzene or a mixture thereof, at -5°C-80°C. Each R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R⁸ и R⁹ independently represents a hydrogen atom, a halogen atom, (C1-C4) alkyl or (C1-C4) alkoxy. The proposed method does not require a very low temperature and is cost-efficient and environmentally friendly.

EFFECT: invention also relates to the preparation method of a compound with formula (5).

29 cl, 2 tbl, 31 ex