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2 792 376

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IPC

C07D499/87(2006-01-01)

A61K31/431(2006-01-01)

A61P31/04(2006-01-01)

(21) (22)

Application

2022118103, 2022-07-04

(24)

Start date

2022-07-04

(22)

Actual filing date

2022-07-04

(45)

Published

2023-03-21

(72)

Inventor

Gein Vladimir LeonidovichIgidov Nazim MusabekovichBobrovskaia Olga VasilevnaNovikova Valentina VasilevnaNosova Natalia VladimirovnaIgidov Sergei Nazimovich

(73)

Holder

Federalnoe Gosudarstvennoe Biudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniia Gosudarstvennaia Farmatsevticheskaia Akademiia» Ministerstva Zdravookhraneniia Rossiiskoi Federatsii

METHOD FOR PRODUCING A BIOLOGICALLY ACTIVE SUBSTANCE HAVING ANTIBACTERIAL ACTIVITY, AND A SUBSTANCE OBTAINED BY THIS METHOD Russian patent published in 2023 - IPC C07D499/87 A61K31/431 A61P31/04

Abstract RU 2792376 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a biologically active substance with antibacterial activity and a method for its production. A new derivative of 6-aminopenicillanic acid is obtained — a new, previously undescribed (Z)-6-(2-hydroxy-4-oxo-4-phenylbut-2-enamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (I), which has a high antibacterial effect, and a method for its production is revealed. The compound (I) specified exhibits low toxicity and can be used in medicine.

EFFECT: new derivative of 6-aminopenicillanic acid is obtained that exhibits low toxicity and can be used in medicine.

2 cl, 1 ex, 1 tbl

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RU 2 792 376 C1

Authors

Gein Vladimir Leonidovich

Igidov Nazim Musabekovich

Bobrovskaia Olga Vasilevna

Novikova Valentina Vasilevna

Nosova Natalia Vladimirovna

Igidov Sergei Nazimovich

Dates

2023-03-21—Published

2022-07-04—Filed