4-(2-METHYL-6-{[2-(DIPHENYLAMINO)-2-OXOETHYL]THIO}-4-FUR-2-YL-5-CYANO-1,4-DIHYDROPYRIDINE-3-CARBOXAMIDO)BENZOIC ACID ETHYL ETHER SHOWING ANTI-INFLAMMATORY PROPERTIES Russian patent published in 2023 - IPC C07D405/04 A61K31/443 A61P29/00 

Abstract RU 2792595 C1

FIELD: medicinal chemistry; pharmacology.

SUBSTANCE: invention relates to the use of ethyl ester 4-(2-methyl-6-{[2-(diphenylamino)-2-oxoethyl]thio}-4-fur-2-yl-5-cyano -1,4-dihydropyridine-3-carboxamido)benzoic acid of formula (I) as an anti-inflammatory agent.

EFFECT: advantage of using the compound of formula (I) is its more pronounced anti-inflammatory effect compared to such drugs as indomethacin, diclofenac, meloxicam and metamizole sodium.

1 cl, 3 tbl, 2 ex

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RU 2 792 595 C1

Authors

Krivokolysko Dmitrii Sergeevich

Bibik Elena Iurevna

Batishcheva Galina Aleksandrovna

Krivokolysko Sergei Gennadievich

Frolov Konstantin Aleksandrovich

Dotsenko Viktor Viktorovich

Pankov Andrei Aleksandrovich

Samokish Anna Aleksandrovna

Venidiktova Iuliia Sergeevna

Dates

2023-03-22Published

2022-07-08Filed