FIELD: organic chemistry, microbiology.
SUBSTANCE: invention relates to novel 5-methyl-2-oxo-1-phenyl-4-ethoxycarbonyl-2,3-dihydro-1H-pyrrole-3-spiro-2-(3-benzoyl-4-hydroxy-1-o-hydroxyphenyl-5-oxo-2,5-dihydropyrroles) of the formula (IIIa,b): wherein X means -OCH3; Y means -CH3 (IIIa); X means bromine atom (Br); Y means chlorine atom (Cl) (IIIb). Proposed compounds elicit an antimicrobial activity with respect to gram-positive microflora. Also, invention describes a method for their synthesis.
EFFECT: valuable biological property of compounds.
3 cl, 1 sch, 1 tbl, 3 ex
Title |
Year |
Author |
Number |
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