METHOD FOR EXTRACTION OF POLYPHENOLIC COMPOUNDS FROM MOLDAVIAN DRAGONHEAD Russian patent published in 2023 - IPC A61K36/53 B01D11/02 

FIELD: pharmaceutical industry.

SUBSTANCE: method for the extraction of polyphenolic compounds from the herb Moldavian dragonhead. A method for extracting polyphenolic compounds from Moldavian dragonhead herb, which consists in mixing the plant material with a solvent, wherein the Moldavian dragonhead herb is crushed to a particle size of 2-3 mm, a 40% aqueous solution of a eutectic solvent is added in a ratio of 1:20 g/ml, obtained from the following components with appropriate molar ratios, selected from

Name Component Molar ratio 1 2 DES 1 Citric acid Glucose 1:1 DES2 Choline chloride Urea 1:2 DES3 Choline chloride Lactic acid 1:3 DES 4 Choline chloride Oxalic acid 1:2 DES 5 Choline chloride Propylene glycol 1:2 DES 6 Proline Glycerol 2:5 DES 7 Choline chloride Sorbite 1:1 DES 8 Choline chloride Glycerol 1:2 DES 9 Proline Lactic acid 1:1 DES 10 Choline chloride Lactic acid 1:2 DES 11 Choline chloride Lactic acid 1:4

and after mixing is heated to 40°C in a water bath and the mixture is exposed to ultrasonic radiation with a frequency of 40 kHz, while the effect is carried out for three successive intervals, in each of which, after 5 minutes, the effect is stopped and the mixture is stirred for 30 seconds, and at the end of the third exposure interval, the mixture is cooled to room temperature to obtain the final product.

EFFECT: improving the efficiency of extraction of polyphenolic compounds from the Moldavian dragonhead herb while ensuring the safety of the final product.

1 cl, 10 dwg