FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for extraction of biologically active phenolic acids. Method for extraction of biologically active phenolic acids - rosemary, lithosperm and salvianolic from vegetal raw materials in the form of Lindelofia stylosa, includes preliminary drying and grinding of Lindelofia stylosa stems and leaves, preparation of a eutectic mixture of choline and malonic acid chloride, holding mixture until formation of a transparent homogeneous liquid with subsequent addition of water until formation of extractant, mixing the prepared vegetal raw material with an extractant and extraction of phenolic acids while heating and ultrasonic action to produce an extract of phenolic acids - rosemary, lithospermic and salvianolic, under certain conditions.
EFFECT: method described above allows to expand the range of extracted phenolic acids from the initial vegetal raw materials while ensuring high degree of their extraction and higher environmental friendliness of the method.
1 cl, 3 ex
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Authors
Dates
2021-01-21—Published
2020-02-17—Filed