NEW VARIANT OF PROLINE DEHYDROGENASE AND A METHOD FOR OBTAINING L-VALINE USING IT Russian patent published in 2023 - IPC C12N9/06 C12N15/77 C12P13/08

Abstract RU 2795067 C1

FIELD: biotechnology.

SUBSTANCE: invention is a polypeptide involved in the production of L-valine, consisting of the amino acid sequence represented by SEQ ID NO: 1 in which glycine being the amino acid corresponding to position 834 of SEQ ID NO: 3 is replaced by serine. The invention also relates to a method for the production of L-valine, which includes cultivating in a medium a microorganism Corynebacterium glutamicum containing a polypeptide according to the invention, or a polynucleotide encoding this polypeptide.

EFFECT: obtaining L-valine with a high degree of efficiency.

5 cl, 1 dwg, 3 tbl, 3 ex

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RU 2 795 067 C1

Authors

Bae Jee Yeon

Kim Seon Hye

Yoon Byoung Hoon

Park Goun

Kim Hyo Jin

Kim Hyung Joon

Dates

2023-04-28—Published

2021-04-09—Filed