FIELD: biotechnology.
SUBSTANCE: disclosed is a microorganism producing L-valine, having enhanced activity of dihydroxy acid dehydratase compared to endogenous activity. Also, the microorganism has any one or more of the combinations selected from reduced activity of transaminase C compared to endogenous activity, reduced activity of pyruvate dehydrogenase compared to endogenous activity and reduced activity of citrate synthase compared to endogenous activity. Also disclosed is a method of producing L-valine using said microorganism.
EFFECT: invention enables to obtain L-valine with high output.
15 cl, 11 tbl, 2 ex
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Authors
Dates
2024-07-11—Published
2021-09-01—Filed