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(19)

RU

(11)

2 796 019

(13)

C2

(51)

IPC

C07K16/46(2006-01-01)

C07K16/28(2006-01-01)

A61K39/395(2006-01-01)

A61K45/00(2006-01-01)

A61K47/68(2017-01-01)

A61P1/16(2006-01-01)

A61P13/12(2006-01-01)

A61P17/00(2006-01-01)

A61P37/00(2006-01-01)

(21) (22)

Application

2020125508, 2019-02-08

(24)

Start date

2019-02-08

(22)

Actual filing date

2019-02-08

(45)

Published

2023-05-16

(72)

Inventor

Shibayama, ShiroShimbo, TakuyaTezuka, TomoyaThrosby, MarkDe Kruif, Cornelis AdriaanVan Loo, Pieter FokkoKlooster, Rinse

(73)

Holder

Ono Pharmaceutical Co., Ltd.

BISPECIFIC ANTIBODY Russian patent published in 2023 - IPC C07K16/46 C07K16/28 A61K39/395 A61K45/00 A61K47/68 A61P1/16 A61P13/12 A61P17/00 A61P37/00 

Abstract RU 2796019 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to a bispecific antibody against PD-1/CD3. Also a pharmaceutical composition for the prevention, suppression of symptoms of progression or recurrence of autoimmune diseases, using the specified antibody is disclosed.

EFFECT: invention allows to carry out effective prophylaxis, suppress symptoms of progression or recurrence of autoimmune diseases.

36 cl, 19 dwg, 15 ex

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RU 2 796 019 C2

Authors

Shibayama, Shiro

Shimbo, Takuya

Tezuka, Tomoya

Throsby, Mark

De Kruif, Cornelis Adriaan

Van Loo, Pieter Fokko

Klooster, Rinse

Dates

2023-05-16—Published

2019-02-08—Filed

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