TLR8 AGONIST Russian patent published in 2023 - IPC C07D471/04 A61K31/519 A61P31/12 

Abstract RU 2800877 C2

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to a compound represented by formula (I), its isomer or its pharmaceutically acceptable salt, where the carbon atom with the sign "*" may be a chiral carbon atom present in the form of one (R) or (S) enantiomer or in the form enriched with one enantiomer; X is CH; R1 is H; R2 is C1-6-alkyl. The invention also relates to a pharmaceutical composition for treating or preventing the development of a disease treatable by TLR8 agonism based on a compound of formula (I).

EFFECT: obtaining a new compound and a pharmaceutical composition based on it, which can be used in medicine for the treatment of a viral infection caused by the hepatitis B virus.

12 cl, 3 tbl, 1 ex

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RU 2 800 877 C2

Authors

Cai, Zhe

Sun, Fei

Ding, Charles Z.

Chen, Shuhui

Dates

2023-07-31Published

2019-09-19Filed