INSTALLATION FOR CONTINUOUS PRODUCTION OF PURIFIED PARACETAMOL, METHOD FOR CONTINUOUS PRODUCTION OF PURIFIED PARACETAMOL Russian patent published in 2023 - IPC C07C231/24 B01D9/02 C07C233/25 

FIELD: organic chemistry.

SUBSTANCE: invention relates to organic chemistry, specifically to a method and installation for purification of technical paracetamol. The method for continuous purification of paracetamol includes: a) obtaining a saturated solution of paracetamol with a concentration of 92-105 g/l by dissolving technical paracetamol in water at a temperature of 75-80° while stirring; b) obtaining mother liquor by adding an antioxidant solution in depleted mother liquor to the resulting saturated solution at the rate of 0.1-1 wt.% of the amount of purified technical paracetamol; c) filtering the resulting mother liquor; d) crystallization of the mother liquor obtained in step (c) in the crystallizer by cooling it to a temperature of 5-25°C to obtain crystals of purified paracetamol and depleted mother liquor, while before supplying the hot mother liquor obtained in step (c), the crystallizer is seeded with crystals of pure paracetamol; e) directing the depleted mother liquor obtained in step (d) to steps (b) and (e); f) washing the purified paracetamol crystals in a pulse column with lean mother liquor stream and separating the crystals by size. Device for continuous purification of paracetamol includes a hopper for technical paracetamol; a reactor for obtaining a mother solution of paracetamol; mother liquor filtration system; overflow; crystallizer; pulse column.

EFFECT: production of paracetamol crystals of the required size, provision of a method for continuous production of a product with a purity of more than 99%, absence of wastewater (liquid waste) and the need for disposal thereof, reducing the time and energy consumption of the process.

13 cl, 4 dwg, 2 ex