COMPOSITIONS AND METHODS OF TREATING EYE DISORDERS Russian patent published in 2023 - IPC A61K31/00 A61K36/75 A61P27/02 

Abstract RU 2802365 C2

FIELD: medicine, ophthalmology.

SUBSTANCE: group of inventions is intended for the treatment of an eye disease or condition. The method of producing/release/delivering/discharge of mucin from the cornea and/or into the cornea includes the step of administering a composition containing a safe and effective amount of an extract having retinol-like properties and/or beneficial effects for use in the treatment of dry eye syndrome, selected from one or more of plant extracts or sources of extracts containing Acronychia acidula. In other embodiments, a method is provided to maintain the concentration of MU5AC in tear fluid in the range of 8 to 15 ng per 1 milligram of protein or higher; a method of treating a patient with reduced or low production/release/delivery/discharge of mucin from the cornea and/or into the cornea; a method of preventing or treating symptoms of dry eye syndrome; and a method of improving the antimicrobial properties of a patient's lacrimal fluid.

EFFECT: using the invention allows to induce, stimulate and/or improve the production/release/delivery/discharge of hyaluronic acid from the cornea and/or into the cornea.

5 cl, 2 dwg, 5 tbl, 7 ex

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Authors

Li, Ven-Khva Tin

Makhmud, Kkhalid

Parsa, Ramin

Baj, Mintsi

Kholeva, Kennet T.

Dates

2023-08-28Published

2019-07-24Filed